Publications

Background On-site delivery of bioactive agents facilitates enhancing the effectiveness of spinal fusion. However, the FDA-approved...

Recombinant human bone morphogenetic protein-2 (rhBMP-2) has been FDA-approved for lumbar fusion, but supraphysiologic initial burst...

Fracture fixation in an ageing population is challenging and fixation failure increases mortality and societal costs. We report a novel...

Despite the glimmer of hope provided by the discovery and commercialization of bone morphogenetic protein-2 (BMP-2) as a bone graft...

Hydroxyapatite (HA) has been widely used as a bone substitute and more recently as a carrier for local delivery of bone targeted drugs....

Cement augmentation of pedicle screws is one of the most promising approaches to enhance the anchoring of screws in the osteoporotic...

A number of techniques have been developed to improve the immediate mechanical anchorage of implants for enhancing implant longevity....

Background The treatments for trochanteric fractures try to regain early mobility and limit morbidity and risk of re-operations. The most...

Pertrochanteric fractures (TF) due to osteoporosis constitute nearly half of all proximal femur fractures. TFs are treated with a...

Per trochanteric fractures are common in an ageing population with osteoporosis and account for about half of all hip fractures....

This research aims to investigate nonionic hyperbranched polyesters (HBPs) derived from indole and lignin resources as new nontoxic...

Due to the aging population, hip fracture incidence has been increasing over the past decades. Measurements of bone mineral density with...

The bone tissue formed at the contact interface with metallic implants, particularly its 3D microstructure, plays a pivotal role for the...

CaS/HA can improve the fixation of a dynamic hip screw.

Ceramic biomaterials are promising alternatives to bone autografts. However, limited bioactivity affects their performance. Therefore,...

Bone morphogenic proteins (BMPs) are the only true osteoinductive molecules. Despite being tremendously potent, their clinical use has...

Osteoporosis often leads to fragility fractures of the hip, resulting in impaired quality of life and increased mortality. Augmenting the...

Bone is a dynamic tissue with a quarter of the trabecular and a fifth of the cortical bone being replaced continuously each year in a...